The Effect of Genetic Factors and Physical Activity on the Incidence of Hypertension among the Productive-Age Population in Kedungwuni Timur Village, Kedungwuni District, Pekalongan Regency

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Pekalongan– Physical Activity and Genetic Factors Not Linked to Hypertension in Productive-Age Adults. This study was conducted by Alvatika Qurnia, Imam Purnomo, and Nur Lu'lu from the Public Health Study Program, Faculty of Health Sciences, University of Pekalongan and published in the International Journal of Education and Life Sciences (IJELS) Vol. 4 No. 2 (February 2026).

The research conducted by Alvatika Qurnia, Imam Purnomo, and Nur Lu'lu shows that two factors that have been considered the main triggers—physical activity and genetic factors—have not been proven to have a significant effect on the incidence of hypertension in the 15–59 age group.

Hypertension Increasing Among Working-Age Population

Data from the Indonesian Health Survey (SKI) 2023 show that hypertension is no longer limited to older adults. Prevalence among those aged 15–20 years reached 10.7 percent, while in the 25–34 age group it was 17.4 percent. Globally, the World Health Organization estimates that 33 percent of the world’s population has hypertension, with two-thirds of cases occurring in low- and middle-income countries.

In Central Java Province, hypertension prevalence stands at 37.57 percent, with slightly higher rates among women than men.

High incidence among productive-age adults raises concerns about reduced work productivity, increased economic burden on families, and rising pressure on healthcare services.

Case-Control Study of 100 Respondents

The study used an analytic observational case–control design involving:

  • 50 respondents with hypertension (case group)
  • 50 respondents without hypertension (control group)

Data were collected through structured interviews and blood pressure measurements. Chi-square tests were used to examine the relationship between physical activity, genetic factors, and hypertension incidence.

Most respondents were aged 44–48 years (27 percent), and the majority had a junior high school educational background (57 percent).

Majority Reported Light Physical Activity

Univariate analysis showed:

  • 57 percent engaged in light physical activity
  • 27 percent engaged in moderate activity
  • 16 percent engaged in vigorous activity

Meanwhile, 55 percent reported a family history of hypertension, and 45 percent did not.

No Significant Association Found

Bivariate analysis results indicate:

  • Physical activity: p = 0.109 (>0.05)
  • Genetic factors: p = 0.230 (>0.05)

These findings demonstrate no statistically significant relationship between physical activity or genetic history and hypertension incidence among the productive-age population in Kedungwuni Timur Village in 2025.

The Odds Ratio for light-to-moderate physical activity was 2.385 with a confidence interval crossing 1, indicating it is not a confirmed risk factor. Genetic factors yielded an OR of 1.758, also statistically insignificant.

Multifactorial Nature of Hypertension

Researchers explain that most respondents had relatively similar activity patterns, primarily routine daily work activities, resulting in limited variability in physical activity levels.

Although genetic predisposition can increase susceptibility to hypertension, it does not independently determine the condition. Other factors such as age, high salt intake, stress, obesity, and smoking may play a more dominant role.

The findings align with previous studies that also reported no significant association between physical activity or hereditary factors and hypertension in certain populations.

Field Challenges During Research

Several practical challenges were encountered:

  • Working-age respondents were often unavailable during daytime visits
  • Some respondents with lower educational backgrounds required additional explanation during interviews
  • Potential recall bias when reporting family history

Despite these obstacles, support from village authorities and the local public health center facilitated data collection.

Policy and Public Health Implications

The study underscores that hypertension prevention strategies should not focus solely on physical activity and genetic predisposition.

Effective prevention should include:

  • Public health education
  • Reduced salt consumption
  • Stress management
  • Regular blood pressure screening
  • Promotion of healthy lifestyle behaviors

Primary healthcare centers are encouraged to strengthen preventive and promotive programs targeting working-age adults.

Conclusion

The study conducted in Kedungwuni Timur Village found no significant effect of physical activity or genetic factors on hypertension incidence among adults aged 15–59 years in 2025.

The findings reinforce the understanding that hypertension is a multifactorial disease influenced by a combination of lifestyle, environmental, and biological factors rather than single determinants.

Comprehensive lifestyle-based prevention remains the most effective strategy for controlling hypertension in the community.

Author Profiles

  • Alvatika Qurnia- Universitas Pekalongan.
  • Imam Purnomo & Nur Lu’lu- Universitas Pekalongan

Research Source

Qurnia, A., Purnomo, I., & Lu’lu, N. (2026). The Effect of Genetic Factors and Physical Activity on the Incidence of Hypertension among the Productive-Age Population in Kedungwuni Timur Village, Kedungwuni District, Pekalongan Regency. International Journal of Education and Life Sciences (IJELS), Vol. 4 No. 2, 185–198. DOI: https://doi.org/10.59890/ijels.v4i2.274

URL: https://ntlmultitechpublisher.my.id/index.php/ijels


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